LINDSAY J. GUERDRUM (1), Charles W. Bamforth (1)
(1) Department of Food Science and Technology, University of California, Davis, CA
About 1% of the Western population suffers from celiac disease, 
making it one of the largest food sensitivities in the world. celiac 
disease is an inherited immune-mediated enteropathy that damages the 
small intestine, thereby interfering with nutrient absorption upon 
consumption of gluten. Patients with celiac disease must abide by a 
strict gluten-free diet void of wheat, rye, barley, and possibly oats. 
Clinical sensitivity toward gluten differs considerably among patients 
but the current Codex Alimentarius standard for a food to be labeled as 
gluten-free is no more than 20 ppm gluten. As most beers are brewed from
 barley- or wheat-based grists, it has long been inferred that they are 
not suitable for people suffering from Celiac disease. However the 
veracity of this conclusion has been questioned, bearing in mind the 
considerable amount of protein modification and removal that occurs 
during malting and brewing. Review of the available methodology 
concluded that the most reliable procedure that ensures quantification 
of all the relevant proteinaceous material (including degradation 
products) is the so-called competitive R5 ELISA method. This method was 
used to assess the levels of gliadin in commercially available beers 
spanning the range of grist material. Gliadin levels ranged from <3 
mg/L for gluten-free beers to 145.8 mg/L for filtered American pale 
wheat beers. With regards to the Codex Alimentarius standard, 10 of the 
28 beers tested were within the guidelines. Many well-known brands in 
the United States have very low levels of detectable gliadin. The key 
brewing factors that impact gliadin levels are presented.
Lindsay Guerdrum received a B.S. degree in biochemistry from the 
University of New Mexico in Albuquerque. She is currently in her second 
year as a food science and technology master’s student at the University
 of California, Davis. During the summer of 2010 she worked as an intern
 for Anheuser-Busch InBev in Fairfield, CA.
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