VIEW ARTICLE    DOI: 10.1094/ASBCJ-42-0173

NOTE Detection and Determination Limits for Chromatographic Systems. T. J. Kieckhefer and J. H. Munroe, Miller Brewing Co., Milwaukee, WI 53201. J. Am. Soc. Brew. Chem. 42:0173, 1984.

A method is described for estimating the standard deviation of the blank signal from chromatographic systems with continuous baselines in order to determine limits of detection and determination. The method is specific for quantitation by peak height and requires sampling the baseline at intervals over a suitable time period.

Keywords: Chromatographic systems, Detection limit, Determination limit, Peak heights