P-11

Thermoanalytical approach to identification of foreign substances in beer.
KAZUTOSHI KITAI, Minoru Kobayashi, Yuji Onagawa, Isao Nadaoka, Yutaka Miyamoto, and Hiroshi Yamashita. Analytical Technology Laboratory, Asahi Breweries Ltd., 1-1-21, Midori, Moriya, Ibaraki, 302-0106, Japan.

For the past several years, the number of complaints brought by consumers has been increasing rapidly in Japan, as they become more aware of the quality and safety of food products. One of the most predominant cases of complaints is the alleged contamination of foreign substances in the products. To deal with the complaint amicably and alleviate the misunderstanding, it is important to provide customers with swift and detailed feedback. On extremely rare occasions, foreign substances are found from raw materials and work-in-process products in the breweries. In the latter cases, the rapid determination of the identity and source of contamination is essential to prevent a problem from recurring. But we encountered difficulties with the conventional analytical methods in the following cases: 1) A trace amount of foreign substance is analyzed; 2) Time-consuming procedures are involved; 3) The risk of sample loss and inadvertent contamination during analysis is conceivable; 4) Samples are not dissolved in any solvents. To overcome these difficulties, we have developed new methods for the analysis of foreign substances. For this purpose, we evaluated the thermal analysis methods, using pyrolizer and GC/MS systems, such as thermal desorption-GC/MS, pyrolysis-GC/MS and reactive pyrolysis-GC/MS. In this investigation, the specific peaks or the chromatographic profiles were obtained from foreign substances and compared with those from the references. As a consequence, it was demonstrated that the identity and, in some cases, the source of contamination were successfully determined for various unknown samples. In our presentation, we will illustrate some applications of the Py-GC/MS to the identification of foreign substances, including synthetic high-polymers such as rubbers and plastics, and natural organic compounds such as polyphenols and lipids. Our newly developed methods have overcome the four difficulties described earlier and provide practical solutions to the analysis of foreign substances. It should also be noted that they are well suited to characterizing unknown trace materials and complex compounds. In addition, our methods offer the following advantages: 1) As little as 1 microgram sample can be analyzed; 2) The analysis is performed easily and swiftly within approximately 20 minutes; 3) The risk of sample loss and contamination is low; 4) Solvents are not required for analysis.

Kazutoshi Kitai graduated from the University of Tokyo with a masters degree, Department of Applied Biological Chemistry, and joined Asahi Breweries Ltd. in 1996. He has been engaged in research and development of brewing technology, especially in analytical chemistry.

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