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Investigations into development of an analytical fingerprint method for beer semivolatile analysis.
DAVID J. MARADYN and Kristian Rogers. Labatt-Interbrew North America, London, ON, Canada.

For a brewer to provide their customer with a consistent and defect-free product, it would be ideal to monitor the concentrations of all chemical compounds that constitute the beer, ensuring each batch is the same as the last. Realistically, it is not practical to measure all chemical compounds in each beer brewed, so what is frequently done is to measure a select number of compounds which yield a chemical "fingerprint" of the particular liquid. Based on the raw ingredients used, the brewing conditions applied and the yeast utilized for fermentation, each beer should have a different "fingerprint." Components selected are not necessarily the most appearance, aroma or flavour active, but ones present in high enough concentration to make their quantification fairly straightforward, with any major problems associated with the liquid quality detected in changes in their concentrations and respective ratios. The usefulness of performing such an analysis is to monitor product consistency and quality when one is changing brewing ingredients and/or instituting a process change or modification, rather than a daily quality control check. This presentation will outline our research into the development of an analytical fingerprint method for semivolatile analytes in finished beer on a gas chromatograph, with special emphasis placed on investigating different sample preparation techniques. The method is capable of quantifying twenty-one different semivolatile compounds, including alcohols, diols, acids, esters and ketones. Studied were liquid-liquid extraction with solvents of varying polarity, solid phase extraction (SPE) with different bonded phases and solid phase microextraction (SPME) with various fiber types. Capillary GC columns spanning a variety of bonded phases were evaluated to maximize analyte resolution. Each method variation was compared and evaluated under the following criteria: ease of analysis, time per analyses, number of analytes detected, cost per analysis and precision and reproducibility of the results. It was concluded that liquid-liquid extraction with ethyl acetate followed by analyte separation on a DB-Wax capillary column was the methodology of choice, based upon our study.

David Maradyn received a B.Sc. in Chemistry in 1991 and a Ph.D. in Organic Chemistry in 1996 from the University of Western Ontario, in London, Ontario, Canada. He joined the Labatt Brewing Company as a Post Doctoral Fellow in 1995, working in the Technology Development Department. Since October 1997, he has been working as a Research Scientist at Labatt, with a focus on analytical method development. David has served the ASBC as member and chairman of technical subcommittees and is currently a member of the Technical Committee.

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